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| Cornell Big Red vs Binghamton Bearcats | Wednesday, November 10, 2021 | 7:30 PM EST | Events Center (Binghamton) in Binghamton, NY | ESPN+ |
| Binghamton Bearcats vs Sacred Heart Pioneers | Sunday, November 14, 2021 | 2:00 PM EST | William H. Pitt Center in Fairfield, CT | ESPN+ |
| Binghamton Bearcats vs Columbia Lions | Wednesday, November 17, 2021 | 7:00 PM EST | Francis S. Levien Gymnasium in New York, NY | ESPN+ |
| Binghamton Bearcats vs Saint Joseph’s Hawks | Wednesday, December 1, 2021 | 7:00 PM EST | Michael J. Hagan ’85 Arena in Philadelphia, PA | ESPN+ |
| Marist Red Foxes vs Binghamton Bearcats | Thursday, December 9, 2021 | 7:00 PM EST | Events Center (Binghamton) in Binghamton, NY | ESPN+ |
| Niagara Purple Eagles vs Binghamton Bearcats | Wednesday, December 22, 2021 | 7:00 PM EST | Events Center (Binghamton) in Binghamton, NY | ESPN+ |
| UMass Lowell River Hawks vs Binghamton Bearcats | Sunday, January 2, 2022 | 2:00 PM EST | Events Center (Binghamton) in Binghamton, NY | ESPN+ |
| Binghamton Bearcats vs Albany Great Danes | Wednesday, January 5, 2022 | 7:00 PM EST | SEFCU Arena in Albany, NY | ESPN+ |
| NJIT Highlanders vs Binghamton Bearcats | Saturday, January 8, 2022 | 4:00 PM EST | Events Center (Binghamton) in Binghamton, NY | ESPN+ |
| Hartford Hawks vs Binghamton Bearcats | Thursday, January 13, 2022 | 7:00 PM EST | Events Center (Binghamton) in Binghamton, NY | ESPN+ |
| Binghamton Bearcats vs Maine Black Bears | Sunday, January 16, 2022 | 1:00 PM EST | Cross Insurance Center in Bangor, ME | ESPN+ |
| Stony Brook Seawolves vs Binghamton Bearcats | Thursday, January 20, 2022 | 7:00 PM EST | Events Center (Binghamton) in Binghamton, NY | ESPN+ |
| Binghamton Bearcats vs NJIT Highlanders | Sunday, January 23, 2022 | 7:00 PM EST | NJIT Wellness and Events Center in Newark, NJ | ESPN+ |
| Binghamton Bearcats vs Hartford Hawks | Thursday, January 27, 2022 | 7:00 PM EST | Chase Arena in West Hartford, CT | ESPN+ |
| Maine Black Bears vs Binghamton Bearcats | Saturday, February 5, 2022 | 2:00 PM EST | Events Center (Binghamton) in Binghamton, NY | ESPN+ |
| Binghamton Bearcats vs Vermont Catamounts | Thursday, February 10, 2022 | 7:00 PM EST | Patrick Gymnasium in Burlington, VT | ESPN+ |
| New Hampshire Wildcats vs Binghamton Bearcats | Saturday, February 12, 2022 | 2:00 PM EST | Events Center (Binghamton) in Binghamton, NY | ESPN+ |
| Binghamton Bearcats vs UMass Lowell River Hawks | Saturday, February 19, 2022 | 7:00 PM EST | Costello Athletic Center in Lowell, MA | ESPN+ |
| Vermont Catamounts vs Binghamton Bearcats | Thursday, February 24, 2022 | 7:00 PM EST | Events Center (Binghamton) in Binghamton, NY | ESPN+ |
| Binghamton Bearcats vs New Hampshire Wildcats | Saturday, February 26, 2022 | 7:00 PM EST | Lundholm Gymnasium in Durham, NH | ESPN+ |
| Binghamton Bearcats vs UMBC Retrievers | Wednesday, March 2, 2022 | 7:00 PM EST | UMBC Event Center in Baltimore, MD | ESPN+ |
