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| Bucknell Bison vs NC State Wolfpack | Tuesday, November 9, 2021 | 5:00 PM EST | PNC Arena in Raleigh, NC | ESPN+ |
| Penn Quakers vs Bucknell Bison | Sunday, November 14, 2021 | 2:00 PM EST | Sojka Pavilion in Lewisburg, PA | ESPN+ |
| Rider Broncs vs Bucknell Bison | Wednesday, November 17, 2021 | 7:00 PM EST | Sojka Pavilion in Lewisburg, PA | ESPN+ |
| Mercer Bears vs Bucknell Bison | Tuesday, November 23, 2021 | 3:00 PM EST | Hard Rock Hotel Riviera Maya in Cancun, Mexico | ESPN+ |
| Siena Saints vs Bucknell Bison | Sunday, November 28, 2021 | 2:00 PM EST | Sojka Pavilion in Lewisburg, PA | ESPN+ |
| Bucknell Bison vs Saint Francis Red Flash | Wednesday, December 1, 2021 | 7:00 PM EST | DeGol Arena in Loretto, PA | ESPN+ |
| Bucknell Bison vs Princeton Tigers | Tuesday, December 7, 2021 | 7:00 PM EST | Jadwin Gymnasium in Princeton, NJ | ESPN+ |
| La Salle Explorers vs Bucknell Bison | Saturday, December 18, 2021 | 2:00 PM EST | Sojka Pavilion in Lewisburg, PA | ESPN+ |
| Bucknell Bison vs Richmond Spiders | Wednesday, December 22, 2021 | 4:00 PM EST | Robins Center in Richmond, VA | ESPN+ |
| Bucknell Bison vs Albany Great Danes | Wednesday, December 29, 2021 | 7:00 PM EST | SEFCU Arena in Albany, NY | ESPN+ |
| Bucknell Bison vs Navy Midshipmen | Friday, January 7, 2022 | 7:00 PM EST | Alumni Hall (Navy) in Annapolis, MD | ESPN+ |
| Lehigh Mountain Hawks vs Bucknell Bison | Thursday, January 13, 2022 | 7:00 PM EST | Sojka Pavilion in Lewisburg, PA | ESPN+ |
| Colgate Raiders vs Bucknell Bison | Wednesday, January 19, 2022 | 7:00 PM EST | Sojka Pavilion in Lewisburg, PA | ESPN+ |
| Bucknell Bison vs Holy Cross Crusaders | Saturday, January 22, 2022 | 2:00 PM EST | Hart Center in Worcester, MA | ESPN+ |
| Navy Midshipmen vs Bucknell Bison | Wednesday, January 26, 2022 | 7:00 PM EST | Sojka Pavilion in Lewisburg, PA | ESPN+ |
| Holy Cross Crusaders vs Bucknell Bison | Saturday, February 12, 2022 | 7:00 PM EST | Sojka Pavilion in Lewisburg, PA | ESPN+ |
