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| Cal State Fullerton Titans vs Santa Clara Broncos | Tuesday, November 9, 2021 | 6:45 PM EST | Leavey Center in Santa Clara, CA | ESPN+ |
| Cal State Fullerton Titans vs San Jose State Spartans | Thursday, November 11, 2021 | 6:30 PM EST | Provident Credit Union Event Center in San Jose, CA | ESPN+ |
| George Washington Colonials vs Cal State Fullerton Titans | Wednesday, November 17, 2021 | 10:30 PM EST | Titan Gym in Fullerton, CA | ESPN+ |
| UTRGV Vaqueros vs Cal State Fullerton Titans | Wednesday, November 24, 2021 | 9:00 PM EST | J. Lawrence Walkup Skydome in Flagstaff, AZ | ESPN+ |
| Cal State Fullerton Titans vs Northern Arizona Lumberjacks | Thursday, November 25, 2021 | 8:00 PM EST | J. Lawrence Walkup Skydome in Flagstaff, AZ | ESPN+ |
| Wyoming Cowboys vs Cal State Fullerton Titans | Tuesday, November 30, 2021 | 10:00 PM EST | Titan Gym in Fullerton, CA | ESPN+ |
| Cal State Fullerton Titans vs San Diego State Aztecs | Wednesday, December 8, 2021 | 7:00 PM EST | Viejas Arena in San Diego, CA | ESPN+ |
| Cal State Fullerton Titans vs CSU Bakersfield Roadrunners | Thursday, December 30, 2021 | 7:00 PM EST | Icardo Center in Bakersfield, CA | ESPN+ |
| Long Beach State 49ers vs Cal State Fullerton Titans | Wednesday, January 5, 2022 | 10:00 PM EST | Titan Gym in Fullerton, CA | ESPN+ |
| Hawaii Warriors vs Cal State Fullerton Titans | Friday, January 7, 2022 | 10:00 PM EST | Titan Gym in Fullerton, CA | ESPN+ |
| Cal State Northridge Matadors vs Cal State Fullerton Titans | Friday, January 14, 2022 | 10:00 PM EST | Titan Gym in Fullerton, CA | ESPN+ |
| UC Santa Barbara Gauchos vs Cal State Fullerton Titans | Sunday, January 16, 2022 | 9:00 PM EST | Titan Gym in Fullerton, CA | ESPN+ |
| Cal State Fullerton Titans vs UC Irvine Anteaters | Friday, January 21, 2022 | 10:00 PM EST | Bren Events Center in Irvine, CA | ESPN+ |
| San Diego Toreros vs Cal State Fullerton Titans | Sunday, January 23, 2022 | 9:00 PM EST | Titan Gym in Fullerton, CA | ESPN+ |
| Cal State Fullerton Titans vs UC Davis Aggies | Friday, January 28, 2022 | 9:00 PM EST | The Pavilion (UC Davis) in Davis, CA | ESPN+ |
| Cal Poly Mustangs vs Cal State Fullerton Titans | Friday, February 4, 2022 | 10:00 PM EST | Titan Gym in Fullerton, CA | ESPN+ |
| CSU Bakersfield Roadrunners vs Cal State Fullerton Titans | Sunday, February 6, 2022 | 9:00 PM EST | Titan Gym in Fullerton, CA | ESPN+ |
| Cal State Fullerton Titans vs Hawaii Warriors | Saturday, February 12, 2022 | 7:00 PM EST | Stan Sheriff Center in Honolulu, HI | ESPN+ |
| Cal State Fullerton Titans vs Cal State Northridge Matadors | Saturday, February 19, 2022 | 7:00 PM EST | Matadome in Northridge, CA | ESPN+ |
| UC Irvine Anteaters vs Cal State Fullerton Titans | Friday, February 25, 2022 | 10:00 PM EST | Titan Gym in Fullerton, CA | ESPN+ |
| Cal State Fullerton Titans vs San Diego Toreros | Sunday, February 27, 2022 | 10:00 PM EST | RIMAC Arena in San Diego, CA | ESPN+ |
| UC Riverside Highlanders vs Cal State Fullerton Titans | Friday, March 4, 2022 | 10:00 PM EST | Titan Gym in Fullerton, CA | ESPN+ |
