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| Gardner-Webb Bulldogs vs UNLV Runnin’ Rebels | Wednesday, November 10, 2021 | 6:30 PM EST | Thomas & Mack Center in Las Vegas, NV | ESPN+ |
| Gardner-Webb Bulldogs vs Arkansas Razorbacks | Saturday, November 13, 2021 | 8:00 PM EST | Bud Walton Arena in Fayetteville, AR | ESPN+ |
| Gardner-Webb Bulldogs vs Duke Blue Devils | Tuesday, November 16, 2021 | 7:00 PM EST | Cameron Indoor Stadium in Durham, NC | ESPN+ |
| Western Carolina Catamounts vs Gardner-Webb Bulldogs | Saturday, November 27, 2021 | 7:00 PM EST | Paul Porter Arena in Boiling Springs, NC | ESPN+ |
| Gardner-Webb Bulldogs vs North Carolina Central Eagles | Monday, November 29, 2021 | 7:00 PM EST | McDougald-McLendon Arena in Durham, NC | ESPN+ |
| Wofford Terriers vs Gardner-Webb Bulldogs | Wednesday, December 8, 2021 | 7:00 PM EST | Paul Porter Arena in Boiling Springs, NC | ESPN+ |
| Gardner-Webb Bulldogs vs VMI Keydets | Saturday, December 11, 2021 | 1:00 PM EST | Cameron Hall in Lexington, VA | ESPN+ |
| North Carolina Central Eagles vs Gardner-Webb Bulldogs | Thursday, December 16, 2021 | 7:00 PM EST | Paul Porter Arena in Boiling Springs, NC | ESPN+ |
| Gardner-Webb Bulldogs vs Georgia Bulldogs | Wednesday, December 29, 2021 | 7:00 PM EST | Stegeman Coliseum in Athens, GA | ESPN+ |
| Gardner-Webb Bulldogs vs Charleston Southern Buccaneers | Wednesday, January 5, 2022 | 7:00 PM EST | Buccaneer Fieldhouse in Charleston, SC | ESPN+ |
| Hampton Pirates vs Gardner-Webb Bulldogs | Saturday, January 8, 2022 | 7:00 PM EST | Paul Porter Arena in Boiling Springs, NC | ESPN+ |
| Presbyterian Blue Hose vs Gardner-Webb Bulldogs | Wednesday, January 12, 2022 | 7:00 PM EST | Paul Porter Arena in Boiling Springs, NC | ESPN+ |
| Gardner-Webb Bulldogs vs Longwood Lancers | Saturday, January 15, 2022 | 7:00 PM EST | Willett Hall in Farmville, VA | ESPN+ |
| USC Upstate Spartans vs Gardner-Webb Bulldogs | Wednesday, January 19, 2022 | 7:00 PM EST | Paul Porter Arena in Boiling Springs, NC | ESPN+ |
| Gardner-Webb Bulldogs vs Winthrop Eagles | Saturday, January 22, 2022 | 7:00 PM EST | Winthrop Coliseum in Rock Hill, SC | ESPN+ |
| Gardner-Webb Bulldogs vs UNC Asheville Bulldogs | Wednesday, January 26, 2022 | 7:00 PM EST | Kimmel Arena in Asheville, NC | ESPN+ |
| North Carolina A&T Aggies vs Gardner-Webb Bulldogs | Saturday, February 5, 2022 | 7:00 PM EST | Paul Porter Arena in Boiling Springs, NC | ESPN+ |
| Gardner-Webb Bulldogs vs Campbell Fighting Camels | Wednesday, February 9, 2022 | 7:00 PM EST | John W. Pope Jr. Convocation Center in Buies Creek, NC | ESPN+ |
| Charleston Southern Buccaneers vs Gardner-Webb Bulldogs | Saturday, February 12, 2022 | 7:00 PM EST | Paul Porter Arena in Boiling Springs, NC | ESPN+ |
| Gardner-Webb Bulldogs vs Presbyterian Blue Hose | Saturday, February 19, 2022 | 7:00 PM EST | Ross E. Templeton P.E. Center in Clinton, SC | ESPN+ |
| UNC Asheville Bulldogs vs Gardner-Webb Bulldogs | Wednesday, February 23, 2022 | 7:00 PM EST | Paul Porter Arena in Boiling Springs, NC | ESPN+ |
| Gardner-Webb Bulldogs vs USC Upstate Spartans | Saturday, February 26, 2022 | 7:00 PM EST | G.B. Hodge Center in Spartanburg, SC | ESPN+ |
