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| Buffalo Bulls vs North Texas Mean Green | Monday, November 15, 2021 | 6:30 PM EST | UNT Coliseum in Denton, TX | ESPN+ |
| UT Arlington Mavericks vs North Texas Mean Green | Thursday, November 18, 2021 | 6:30 PM EST | UNT Coliseum in Denton, TX | ESPN+ |
| North Texas Mean Green vs Kansas Jayhawks | Thursday, November 25, 2021 | 2:30 PM EST | HP Field House in Orlando, FL | ESPN+ |
| UMass Minutemen vs North Texas Mean Green | Saturday, December 11, 2021 | 7:00 PM EST | Dickies Arena in Fort Worth, TX | ESPN+ |
| Sam Houston State Bearkats vs North Texas Mean Green | Tuesday, December 14, 2021 | 7:00 PM EST | UNT Coliseum in Denton, TX | ESPN+ |
| North Texas Mean Green vs Wichita State Shockers | Saturday, December 18, 2021 | 7:00 PM EST | Charles Koch Arena in Wichita, KS | ESPN+ |
| UAB Blazers vs North Texas Mean Green | Thursday, January 6, 2022 | 7:00 PM EST | UNT Coliseum in Denton, TX | ESPN+ |
| MTSU Blue Raiders vs North Texas Mean Green | Saturday, January 8, 2022 | 7:00 PM EST | UNT Coliseum in Denton, TX | ESPN+ |
| North Texas Mean Green vs Marshall Thundering Herd | Thursday, January 13, 2022 | 7:00 PM EST | Cam Henderson Center in Huntington, WV | ESPN+ |
| North Texas Mean Green vs Western Kentucky Hilltoppers | Saturday, January 15, 2022 | 7:00 PM EST | E. A. Diddle Arena in Bowling Green, KY | ESPN+ |
| Charlotte 49ers vs North Texas Mean Green | Thursday, January 20, 2022 | 7:00 PM EST | UNT Coliseum in Denton, TX | ESPN+ |
| Old Dominion Monarchs vs North Texas Mean Green | Saturday, January 22, 2022 | 7:00 PM EST | UNT Coliseum in Denton, TX | ESPN+ |
| North Texas Mean Green vs Southern Miss Golden Eagles | Thursday, January 27, 2022 | 7:00 PM EST | Reed Green Coliseum in Hattiesburg, MS | ESPN+ |
| UTEP Miners vs North Texas Mean Green | Thursday, February 3, 2022 | 7:00 PM EST | UNT Coliseum in Denton, TX | ESPN+ |
| UTSA Roadrunners vs North Texas Mean Green | Saturday, February 5, 2022 | 7:00 PM EST | UNT Coliseum in Denton, TX | ESPN+ |
| North Texas Mean Green vs Rice Owls | Saturday, February 12, 2022 | 7:00 PM EST | Tudor Fieldhouse in Houston, TX | ESPN+ |
| North Texas Mean Green vs UAB Blazers | Saturday, February 19, 2022 | 7:00 PM EST | Bartow Arena in Birmingham, AL | ESPN+ |
| Southern Miss Golden Eagles vs North Texas Mean Green | Thursday, February 24, 2022 | 7:00 PM EST | UNT Coliseum in Denton, TX | ESPN+ |
| Louisiana Tech Bulldogs vs North Texas Mean Green | Saturday, February 26, 2022 | 7:00 PM EST | UNT Coliseum in Denton, TX | ESPN+ |
| North Texas Mean Green vs UTSA Roadrunners | Thursday, March 3, 2022 | 7:00 PM EST | UTSA Convocation Center in San Antonio, TX | ESPN+ |
