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| Omaha Mavericks vs Kansas State Wildcats | Wednesday, November 17, 2021 | 7:00 PM EST | Bramlage Coliseum in Manhattan, KS | ESPN+ |
| Omaha Mavericks vs Texas Tech Red Raiders | Tuesday, November 23, 2021 | 7:00 PM EST | United Supermarkets Arena in Lubbock, TX | ESPN+ |
| Omaha Mavericks vs Purdue Boilermakers | Friday, November 26, 2021 | 7:00 PM EST | Mackey Arena in West Lafayette, IN | ESPN+ |
| Southern Illinois Salukis vs Omaha Mavericks | Wednesday, December 1, 2021 | 7:00 PM EST | Baxter Arena in Omaha, NE | ESPN+ |
| Drake Bulldogs vs Omaha Mavericks | Thursday, December 9, 2021 | 8:00 PM EST | Baxter Arena in Omaha, NE | ESPN+ |
| TAMU Islanders vs Omaha Mavericks | Sunday, December 12, 2021 | 7:00 PM EST | Baxter Arena in Omaha, NE | ESPN+ |
| Omaha Mavericks vs UNLV Runnin’ Rebels | Wednesday, December 15, 2021 | 7:00 PM EST | Thomas & Mack Center in Las Vegas, NV | ESPN+ |
| Western Illinois Leathernecks vs Omaha Mavericks | Wednesday, December 22, 2021 | 7:00 PM EST | Baxter Arena in Omaha, NE | ESPN+ |
| North Dakota Fighting Hawks vs Omaha Mavericks | Thursday, January 6, 2022 | 7:00 PM EST | Baxter Arena in Omaha, NE | ESPN+ |
| North Dakota State Bison vs Omaha Mavericks | Saturday, January 8, 2022 | 7:00 PM EST | Baxter Arena in Omaha, NE | ESPN+ |
| Omaha Mavericks vs South Dakota State Jackrabbits | Thursday, January 13, 2022 | 7:00 PM EST | Frost Arena in Brookings, SD | ESPN+ |
| Omaha Mavericks vs South Dakota Coyotes | Saturday, January 15, 2022 | 7:00 PM EST | Sanford Coyote Sports Center in Vermillion, SD | ESPN+ |
| Omaha Mavericks vs Denver Pioneers | Saturday, January 22, 2022 | 3:00 PM EST | Hamilton Gymnasium in Denver, CO | ESPN+ |
| Oral Roberts Golden Eagles vs Omaha Mavericks | Thursday, January 27, 2022 | 7:00 PM EST | Baxter Arena in Omaha, NE | ESPN+ |
| Omaha Mavericks vs North Dakota State Bison | Thursday, February 3, 2022 | 7:00 PM EST | Scheels Center in Fargo, ND | ESPN+ |
| Omaha Mavericks vs North Dakota Fighting Hawks | Saturday, February 5, 2022 | 7:00 PM EST | Betty Engelstad Sioux Center in Grand Forks, ND | ESPN+ |
| South Dakota State Jackrabbits vs Omaha Mavericks | Saturday, February 12, 2022 | 7:00 PM EST | Baxter Arena in Omaha, NE | ESPN+ |
| Denver Pioneers vs Omaha Mavericks | Saturday, February 19, 2022 | 7:00 PM EST | Baxter Arena in Omaha, NE | ESPN+ |
| Omaha Mavericks vs Western Illinois Leathernecks | Friday, February 25, 2022 | 7:00 PM EST | LeRoy A. Ufkes Court at Western Hall in Macomb, IL | ESPN+ |
