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| Sam Houston State Bearkats vs Nebraska Cornhuskers | Saturday, November 13, 2021 | 8:30 PM EST | Pinnacle Bank Arena in Lincoln, NE | ESPN+ |
| Sam Houston State Bearkats vs SMU Mustangs | Wednesday, November 24, 2021 | 7:00 PM EST | Moody Coliseum in Dallas, TX | ESPN+ |
| Sam Houston State Bearkats vs Texas Longhorns | Tuesday, November 30, 2021 | 8:30 PM EST | Frank Erwin Center in Austin, TX | Longhorn Network |
| UTSA Roadrunners vs Sam Houston State Bearkats | Saturday, December 11, 2021 | 7:00 PM EST | Bernard G. Johnson Coliseum in Huntsville, TX | ESPN+ |
| Sam Houston State Bearkats vs North Texas Mean Green | Tuesday, December 14, 2021 | 7:00 PM EST | UNT Coliseum in Denton, TX | ESPN+ |
| Bradley Braves vs Sam Houston State Bearkats | Tuesday, December 21, 2021 | 6:00 PM EST | Don Haskins Center in El Paso, TX | ESPN+ |
| Lamar Cardinals vs Sam Houston State Bearkats | Friday, December 31, 2021 | 7:30 PM EST | Bernard G. Johnson Coliseum in Huntsville, TX | ESPN+ |
| Sam Houston State Bearkats vs Abilene Christian Wildcats | Sunday, January 9, 2022 | 7:00 PM EST | Teague Center in Abilene, TX | ESPN+ |
| Sam Houston State Bearkats vs Lamar Cardinals | Thursday, January 13, 2022 | 7:00 PM EST | Montagne Center in Beaumont, TX | ESPN+ |
| Stephen F. Austin Lumberjacks vs Sam Houston State Bearkats | Saturday, January 15, 2022 | 3:00 PM EST | Bernard G. Johnson Coliseum in Huntsville, TX | ESPN+ |
| New Mexico State Aggies vs Sam Houston State Bearkats | Friday, January 21, 2022 | 7:30 PM EST | Bernard G. Johnson Coliseum in Huntsville, TX | ESPN+ |
| Grand Canyon Antelopes vs Sam Houston State Bearkats | Saturday, January 22, 2022 | 3:00 PM EST | Bernard G. Johnson Coliseum in Huntsville, TX | ESPN+ |
| Sam Houston State Bearkats vs California Baptist Lancers | Friday, January 28, 2022 | 10:00 PM EST | CBU Events Center in Riverside, CA | ESPN+ |
| Dixie State Trailblazers vs Sam Houston State Bearkats | Friday, February 4, 2022 | 7:30 PM EST | Bernard G. Johnson Coliseum in Huntsville, TX | ESPN+ |
| Utah Valley Wolverines vs Sam Houston State Bearkats | Saturday, February 5, 2022 | 3:00 PM EST | Bernard G. Johnson Coliseum in Huntsville, TX | ESPN+ |
| Sam Houston State Bearkats vs Chicago State Cougars | Saturday, February 12, 2022 | 7:00 PM EST | Jones Convocation Center in Chicago, IL | ESPN+ |
| Abilene Christian Wildcats vs Sam Houston State Bearkats | Saturday, February 19, 2022 | 7:00 PM EST | Bernard G. Johnson Coliseum in Huntsville, TX | ESPN+ |
| Sam Houston State Bearkats vs Stephen F. Austin Lumberjacks | Thursday, February 24, 2022 | 7:00 PM EST | William R. Johnson Coliseum in Nacogdoches, TX | ESPN+ |
| Sam Houston State Bearkats vs Grand Canyon Antelopes | Sunday, February 27, 2022 | 8:00 PM EST | GCU Arena in Phoenix, AZ | ESPN+ |
