|
| Robert Morris Colonials vs UCF Knights | Wednesday, November 10, 2021 | 7:00 PM EST | Addition Financial Arena in Orlando, FL | ESPN+ |
| UCF Knights vs Miami Hurricanes | Saturday, November 13, 2021 | 2:00 PM EST | Watsco Center in Coral Gables, FL | ACC Network Extra |
| Jacksonville Dolphins vs UCF Knights | Tuesday, November 16, 2021 | 7:00 PM EST | Addition Financial Arena in Orlando, FL | ESPN+ |
| Oklahoma Sooners vs UCF Knights | Saturday, November 27, 2021 | 7:00 PM EST | Addition Financial Arena in Orlando, FL | ESPN+ |
| UCF Knights vs Auburn Tigers | Wednesday, December 1, 2021 | 7:00 PM EST | Auburn Arena in Auburn, AL | ESPN+ |
| Bethune-Cookman Wildcats vs UCF Knights | Sunday, December 5, 2021 | 2:00 PM EST | Addition Financial Arena in Orlando, FL | ESPN+ |
| North Carolina A&T Aggies vs UCF Knights | Saturday, December 11, 2021 | 7:00 PM EST | Addition Financial Arena in Orlando, FL | ESPN+ |
| UCF Knights vs Temple Owls | Thursday, December 16, 2021 | 7:00 PM EST | Liacouras Center in Philadelphia, PA | ESPN2 |
| UCF Knights vs Florida State Seminoles | Saturday, December 18, 2021 | 7:00 PM EST | FLA Live Arena in Sunrise, FL | ESPN+ |
| North Alabama Lions vs UCF Knights | Wednesday, December 22, 2021 | 7:00 PM EST | Addition Financial Arena in Orlando, FL | ESPN+ |
| Michigan Wolverines vs UCF Knights | Friday, December 31, 2021 | 7:00 PM EST | Addition Financial Arena in Orlando, FL | ESPN2 |
| UCF Knights vs SMU Mustangs | Sunday, January 2, 2022 | 2:00 PM EST | Moody Coliseum in Dallas, TX | ESPNU |
| Temple Owls vs UCF Knights | Wednesday, January 5, 2022 | 7:00 PM EST | Addition Financial Arena in Orlando, FL | ESPN+ |
| Tulsa Golden Hurricane vs UCF Knights | Saturday, January 8, 2022 | 2:00 PM EST | Addition Financial Arena in Orlando, FL | ESPNU |
| Memphis Tigers vs UCF Knights | Wednesday, January 12, 2022 | 7:00 PM EST | Addition Financial Arena in Orlando, FL | ESPN+ |
| UCF Knights vs USF Bulls | Saturday, January 15, 2022 | 7:00 PM EST | Yuengling Center in Tampa, FL | ESPN+ |
| UCF Knights vs East Carolina Pirates | Tuesday, January 18, 2022 | 7:00 PM EST | Williams Arena at Minges Coliseum in Greenville, NC | ESPN+ |
| Tulane Green Wave vs UCF Knights | Saturday, January 22, 2022 | 2:00 PM EST | Addition Financial Arena in Orlando, FL | ESPNU |
| UCF Knights vs Wichita State Shockers | Wednesday, January 26, 2022 | 7:00 PM EST | Charles Koch Arena in Wichita, KS | ESPN+ |
| USF Bulls vs UCF Knights | Thursday, February 3, 2022 | 7:00 PM EST | Addition Financial Arena in Orlando, FL | ESPN+ |
| UCF Knights vs Memphis Tigers | Sunday, February 6, 2022 | 8:00 PM EST | FedExForum in Memphis, TN | ESPN+ |
| UCF Knights vs Houston Cougars | Thursday, February 17, 2022 | 7:00 PM EST | Fertitta Center in Houston, TX | ESPN+ |
| East Carolina Pirates vs UCF Knights | Sunday, February 20, 2022 | 7:00 PM EST | Addition Financial Arena in Orlando, FL | ESPN+ |
| Cincinnati Bearcats vs UCF Knights | Thursday, February 24, 2022 | 9:00 PM EST | Addition Financial Arena in Orlando, FL | ESPNU |
| UCF Knights vs Tulane Green Wave | Thursday, March 3, 2022 | 7:00 PM EST | Avron B. Fogelman Arena in the Devlin Fieldhouse in New Orleans, LA | ESPN+ |
