| Game | Date | Time | Stadium | TV Station |
|---|---|---|---|---|
| Philadelphia Eagles vs Detroit Lions | Sunday, September 11, 2022 | 1:00 PM EST | Ford Field in Detroit, MI | FOX |
| Washington Commanders vs Detroit Lions | Sunday, September 18, 2022 | 1:00 PM EST | Ford Field in Detroit, MI | FOX |
| Detroit Lions vs Minnesota Vikings | Sunday, September 25, 2022 | 1:00 PM EST | U.S. Bank Stadium in Minneapolis, MN | FOX |
| Seattle Seahawks vs Detroit Lions | Sunday, October 2, 2022 | 1:00 PM EST | Ford Field in Detroit, MI | FOX |
| Detroit Lions vs New England Patriots | Sunday, October 9, 2022 | 1:00 PM EST | Gillette Stadium in Foxborough, MA | FOX |
| Detroit Lions vs Dallas Cowboys | Sunday, October 23, 2022 | 1:00 PM EST | AT&T Stadium in Arlington, TX | CBS |
| Miami Dolphins vs Detroit Lions | Sunday, October 30, 2022 | 1:00 PM EST | Ford Field in Detroit, MI | CBS |
| Green Bay Packers vs Detroit Lions | Sunday, November 6, 2022 | 1:00 PM EST | Ford Field in Detroit, MI | FOX |
| Detroit Lions vs Chicago Bears | Sunday, November 13, 2022 | 1:00 PM EST | Soldier Field in Chicago, IL | FOX |
| Detroit Lions vs New York Giants | Sunday, November 20, 2022 | 1:00 PM EST | MetLife Stadium in East Rutherford, NJ | FOX |
| Buffalo Bills vs Detroit Lions | Thursday, November 24, 2022 | 12:30 PM EST | Ford Field in Detroit, MI | CBS |
| Jacksonville Jaguars vs Detroit Lions | Sunday, December 4, 2022 | 1:00 PM EST | Ford Field in Detroit, MI | FOX |
| Minnesota Vikings vs Detroit Lions | Sunday, December 11, 2022 | 1:00 PM EST | Ford Field in Detroit, MI | FOX |
| Detroit Lions vs New York Jets | Sunday, December 18, 2022 | 1:00 PM EST | MetLife Stadium in East Rutherford, NJ | FOX |
| Detroit Lions vs Carolina Panthers | Saturday, December 24, 2022 | 1:00 PM EST | Bank of America Stadium in Charlotte, NC | FOX |
| Chicago Bears vs Detroit Lions | Sunday, January 1, 2023 | 1:00 PM EST | Ford Field in Detroit, MI | FOX |
| Detroit Lions vs Green Bay Packers | Sunday, January 8, 2023 | 1:00 PM EST | Lambeau Field in Green Bay, WI | CBS |
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2021 Detroit Lions TV Broadcast Schedule
| Game | Date | Time | Stadium | TV Station |
|---|---|---|---|---|
| San Francisco 49ers vs Detroit Lions | Sunday, September 12, 2021 | 1:00 PM EST | Ford Field in Detroit, MI | FOX |
| Detroit Lions vs Green Bay Packers | Monday, September 20, 2021 | 8:15 PM EST | Lambeau Field in Green Bay, WI | ESPN |
| Baltimore Ravens vs Detroit Lions | Sunday, September 26, 2021 | 1:00 PM EST | Ford Field in Detroit, MI | CBS |
| Detroit Lions vs Chicago Bears | Sunday, October 3, 2021 | 1:00 PM EST | Soldier Field in Chicago, IL | FOX |
| Detroit Lions vs Minnesota Vikings | Sunday, October 10, 2021 | 1:00 PM EST | U.S. Bank Stadium in Minneapolis, MN | FOX |
| Cincinnati Bengals vs Detroit Lions | Sunday, October 17, 2021 | 1:00 PM EST | Ford Field in Detroit, MI | FOX |
| Detroit Lions vs Los Angeles Rams | Sunday, October 24, 2021 | 4:05 PM EST | SoFi Stadium in Inglewood, CA | FOX |
| Philadelphia Eagles vs Detroit Lions | Sunday, October 31, 2021 | 1:00 PM EST | Ford Field in Detroit, MI | FOX |
| Detroit Lions vs Pittsburgh Steelers | Sunday, November 14, 2021 | 1:00 PM EST | Heinz Field in Pittsburgh, PA | FOX |
| Detroit Lions vs Cleveland Browns | Sunday, November 21, 2021 | 1:00 PM EST | FirstEnergy Stadium in Cleveland, OH | FOX |
| Chicago Bears vs Detroit Lions | Thursday, November 25, 2021 | 12:30 PM EST | Ford Field in Detroit, MI | FOX |
| Minnesota Vikings vs Detroit Lions | Sunday, December 5, 2021 | 1:00 PM EST | Ford Field in Detroit, MI | CBS |
| Detroit Lions vs Denver Broncos | Sunday, December 12, 2021 | 4:05 PM EST | Empower Field at Mile High in Denver, CO | FOX |
| Arizona Cardinals vs Detroit Lions | Sunday, December 19, 2021 | 1:00 PM EST | Ford Field in Detroit, MI | FOX |
| Detroit Lions vs Atlanta Falcons | Sunday, December 26, 2021 | 1:00 PM EST | Mercedes-Benz Stadium in Atlanta, GA | FOX |
| Detroit Lions vs Seattle Seahawks | Sunday, January 2, 2022 | 4:25 PM EST | Lumen Field in Seattle, WA | FOX |
| Green Bay Packers vs Detroit Lions | Sunday, January 9, 2022 | 1:00 PM EST | Ford Field in Detroit, MI | FOX |
