| East Carolina Pirates vs Appalachian State Mountaineers |
Thursday, September 2, 2021 |
7:30 PM EST |
Bank of America Stadium in Charlotte, NC |
ESPNU |
| South Carolina Gamecocks vs East Carolina Pirates |
Saturday, September 11, 2021 |
12:00 PM EST |
Dowdy-Ficklen Stadium in Greenville, NC |
ESPN2 |
| East Carolina Pirates vs Marshall Thundering Herd |
Saturday, September 18, 2021 |
6:00 PM EST |
Joan C. Edwards Stadium in Huntington, WV |
ESPN+ |
| Tulane Green Wave vs East Carolina Pirates |
Saturday, October 2, 2021 |
3:30 PM EST |
Dowdy-Ficklen Stadium in Greenville, NC |
ESPN+ |
| East Carolina Pirates vs UCF Knights |
Saturday, October 9, 2021 |
1:00 PM EST |
Bounce House in Orlando, FL |
ESPN+ |
| East Carolina Pirates vs Houston Cougars |
Saturday, October 23, 2021 |
4:00 PM EST |
TDECU Stadium in Houston, TX |
ESPNU |
| USF Bulls vs East Carolina Pirates |
Thursday, October 28, 2021 |
7:30 PM EST |
Dowdy-Ficklen Stadium in Greenville, NC |
ESPN |
| Temple Owls vs East Carolina Pirates |
Saturday, November 6, 2021 |
3:00 PM EST |
Dowdy-Ficklen Stadium in Greenville, NC |
ESPN+ |
| East Carolina Pirates vs Memphis Tigers |
Saturday, November 13, 2021 |
12:00 PM EST |
Liberty Bowl Memorial Stadium in Memphis, TN |
ESPN+ |
| East Carolina Pirates vs Navy Midshipmen |
Saturday, November 20, 2021 |
3:30 PM EST |
Navy-Marine Corps Memorial Stadium in Annapolis, MD |
CBSSN |
| Cincinnati Bearcats vs East Carolina Pirates |
Friday, November 26, 2021 |
3:30 PM EST |
Dowdy-Ficklen Stadium in Greenville, NC |
ABC |
